【英文名称】Sophora japonica extract
Technical Specifications

【Chinese Name】 槐米提取物
【English Name】 Japanese Pagodatree Extract
【Latin Name】 Styphnolobium japonicum (L.) Schott (syn. Sophora japonica)
【Plant Part Used】 Flower buds
【Standardization】
• Rutin ≥95% (UV/HPLC)
• Quercetin ≥98% (HPLC)
• 10:1 crude extract available
【Appearance】 Brown-yellowish powder
【Active Components】
• Flavonol glycosides (Rutin, Isoquercitrin)
• Aglycones (Quercetin, Kaempferol)
• Sophorabioside

Quality Standards

✓ Heavy Metals: As<1ppm, Pb<2ppm, Cd<0.5ppm
✓ Microbiological: TAMC<1000 CFU/g, TYMC<100 CFU/g
✓ Residual Solvents: Meets ICH Q3C Class 3
✓ Pesticides: Below EU MRLs

Manufacturing Process

1. Ethanol-water      extraction (70:30 v/v)

2. Acid      hydrolysis for quercetin production

3. Crystallization      purification

4. Vacuum      drying (<60°C)

Packaging & Stability

【Primary】 Double aluminum foil bags (1kg)
【Secondary】 Fiber drum with desiccant (25kg)
【Storage】 15-25°C, ≤65% RH, protected from light
【Shelf Life】 24 months

Clinical Applications

Vascular Protection:

• Reduces      capillary fragility (P-vitamin activity)

• Inhibits      LDL oxidation by 72%

Anti-inflammatory:

• COX-2      inhibition comparable to NSAIDs

• Reduces      histamine release

Antidiabetic Effects:

• Aldose      reductase inhibition (prevents diabetic complications)

• Improves      endothelial function