Specifications: 50%, 98%

Appearance: Yellow needle-like crystalline powder

Botanical Source: Cotinus Coggygria Scop

Test Method: HPLC

CAS No: 528-48-3

Fisetin is a type of flavonoid that is insoluble in water, carbon tetrachloride, and petroleum ether but dissolves readily in solvents like acetone and acetic acid. It is naturally abundant in strawberries, apples, onions, cucumbers, and various other fruits and vegetables.

Due to its widespread availability, low cost, and ease of extraction, fisetin has gained attention for its diverse pharmacological properties, including antioxidant, anticoagulant, and antithrombotic effects, as well as its potential in cancer treatment. Recent studies suggest that fisetin exerts anti-tumor effects by inhibiting tumor cell proliferation and signal transduction pathways while promoting tumor cell apoptosis.

Fisetin Function

Fisetin is a naturally occurring flavonoid with a wide range of biological activities and is a promising compound for various therapeutic applications. Its main functions include:

Antioxidant activity

• Neutralizes free radicals and reduces oxidative stress.

• Protects cells from damage caused by reactive oxygen species      (ROS).

Anti-inflammatory effects

• Modulates inflammatory pathways by inhibiting pro-inflammatory      cytokines.

• Reduces chronic inflammation associated with diseases such as      arthritis and neurodegenerative diseases.

Anticancer properties

• Inhibits tumor cell proliferation and metastasis.

• Induces apoptosis (programmed cell death) in cancer cells.

• Inhibits key signaling pathways involved in tumor growth.

Neuroprotective effects

• Enhance cognitive function and memory by promoting neuronal      survival.

• Reduces neuroinflammation, with potential benefits in      Alzheimer’s and Parkinson’s diseases.

• Supports brain health by preventing oxidative damage to      neurons.

Cardiovascular protection

• Has anticoagulant and antithrombotic properties, reducing the      risk of blood clots.

• Lowers blood pressure and improves vascular function.

• Helps reduce cholesterol levels and prevent atherosclerosis.

Antidiabetic effects

• Improve insulin sensitivity and regulate blood sugar levels.

• Protect pancreatic beta cells from damage caused by oxidative      stress.

Fisetin Applications

Fisetin has a variety of pharmacological properties and has been widely studied for use in various fields such as medicine, cosmetics and functional foods. The following are its main applications:

1. Medical applications
2. Cosmetic applications
3. Functional foods and supplements
4. Pharmaceutical research and drug development
5. Antimicrobial and antiviral applications

Why CALnatural Fisetin?

CALnatural is a reputable supplier of high-quality fisetin, with several advantages that make it a top choice for consumers and manufacturers:

High purity and quality control
CALnatural offers fisetin with purity specifications of 50% and 98%, ensuring the product is high quality and suitable for a variety of uses. The company adheres to strict quality assurance protocols, including rigorous independent testing, to ensure the safety and efficacy of the product.

Natural sources
Fisetin is extracted from natural sources, specifically Cotinus coggygria (smoke tree), ensuring the product is free of synthetic additives.

Expertise and experience
CALnatural has been dedicated to the research, production and sales of natural plant extracts for more than a decade and has become a professional custom service provider in the industry. The company has a modern standard factory with a complete plant extract production line and an internationally leading R&D and quality control laboratory.

Global reach and accessibility
CALnatural has offices and warehouses around the world, including a US office in California, ensuring efficient distribution and accessibility for international customers.

By choosing CALNATURAL’s Quercetin, consumers and manufacturers can trust the product’s quality, purity, and the company’s commitment to excellence in natural plant extracts.