Technical Specifications

【Chinese Name】 橄榄叶提取物
【English Name】 Olive Leaf Extract (Standardized Oleuropein)
【Latin Name】 Olea europaea L. (Oleaceae)
【Plant Part Used】 Dried leaves from mature trees
【Standardization】 Oleuropein 10%-80% (adjustable)
【Appearance】 Fine brown powder
【Active Components】
• Secoiridoids (Oleuropein, Ligstroside)
• Phenolic acids (Hydroxytyrosol, Tyrosol)
• Flavonoids (Luteolin, Apigenin)

Quality Control

✓ HPLC-UV quantification (EP 10.0 method)
✓ Heavy Metals: As<1ppm, Pb<2ppm, Cd<0.5ppm
✓ Microbiological: TAMC<1000 CFU/g, TYMC<100 CFU/g
✓ Residual Solvents: Meets ICH Q3C Class 3

Manufacturing Process

1. Ethanol-water      extraction (50:50 v/v)

2. Macroporous      resin purification

3. Low-temperature      concentration (<50°C)

4. Instant      sterilization (UV treatment)

Packaging & Stability

【Primary】 Double aluminum foil bags with oxygen absorber (1kg)
【Secondary】 Reinforced paper drum (25kg)
【Storage】 15-25°C, ≤65% RH, protected from light
【Shelf Life】 24 months (36 months at 2-8°C)

Clinical Benefits

Cardiovascular:

• Reduces      systolic BP by 11.5mmHg in stage-1 hypertension

• Improves      endothelial function (FMD +3.2%)

Metabolic:

• Lowers      fasting glucose by 12% in prediabetics

• Increases      insulin sensitivity (HOMA-IR -15%)

Antimicrobial:

• Effective      against MRSA (MIC 0.6mg/ml oleuropein)

• Antiviral      activity against influenza strains

Regulatory Status

• EFSA Article 13.1 Health Claim
• FDA GRAS Notice GRN 000659
• TCM Approved (China Pharmacopoeia)

*Note: Standardization options include 10%/20%/40%/80% oleuropein. Hydroxytyrosol-enriched versions (5-10%) available.*

For clinical trial references or customized formulations, please request our technical dossier.